Roux-en-Y Gastric Bypass Improved Insulin Resistance via Alteration of the Human Gut Microbiome and Alleviation of Endotoxemia

Figure 3

RYGB downregulates the levels of LBP and increases the formation of SCFAs in obese patients. (a) Serum levels of LBP in obesity patients in preop, post-1 m-op, post-3 m-op, and post-6 m-op group. Serum levels of LBP had decreased after RYGB. (b) Correlation network between LBP and diversity species. Red and purple edges denote Spearman’s rank correlation (red denotes positive correlation, and purple denotes negative correlation), and difference color circles denoted different groups, respectively. Serum levels of LBP existed a positive correlation with diversity species in the preop group and were negative correlated with postop groups. (c) Correlation between adiponectin and LBP. (d) Correlation between adiponectin and HOMA-IR. (e) Correlation between LBP and HOMA-IR. (f) Correlation network between SCFAs and diversity species. Levels of all these SCFAs in feces had negative correlation with diversity species in the preop group and existed positive correlation in postop groups.

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