Research Article
Interaction of Adiponectin Genotypes and Insulin Resistance on the Occurrence of Taiwanese Metabolic Syndrome
Table 2
Association of apM1 +45 and TNF-α -308 genotypes with the development of Taiwanese metabolic syndrome.
| | Variables | With MetS | Without MetS | OR (95% CI)# | | |
| | apM1 +45 genotypes | | TT | 67 (55.4%) | 100 (48.1%) | 1.23 (0.54-2.84) | | TG | 44 (36.3%) | 89 (42.8%) | 0.91 (0.39-2.13) | | GG | 10 (8.3%) | 19 (9.1%) | 1.00 (ref.) | | Dominant model | | TT | 67 (55.4%) | 100 (48.1%) | 1.34 (0.85-2.11) | | TG/GG | 54 (44.6%) | 108 (51.9%) | 1.00 (ref.) | | Recessive model | | TT/TG | 111 (91.7%) | 189 (90.9%) | 1.08 (0.48-2.42) | | GG | 10 (8.3%) | 19 (9.1%) | 1.00 (ref.) | | T allele | 178 (73.6%) | 289 (69.5%) | 1.21 (0.85-1.73) | | G allele | 64 (26.4%) | 127 (30.5%) | 1.00 (ref.) | | TNF-α -308 genotypes | | AA | 1 (0.8%) | 3 (1.4%) | 0.69 (0.07-6.97) | | AG | 25 (20.7%) | 37 (17.8%) | 1.17 (0.66-2.09) | | GG | 95 (78.5%) | 168 (80.8%) | 1.00 (ref.) | | Dominant model | | AA/AG | 26 (21.5%) | 40 (19.2%) | 1.49 (0.15-14.94) | | GG | 95 (78.5%) | 168 (80.8%) | 1.00 (ref.) | | Recessive model | | AA | 1 (0.8%) | 3 (1.4%) | 0.67 (0.07-6.75) | | AG/GG | 120 (99.2%) | 205 (98.6%) | 1.00 (ref.) | | A allele | 27 (11.2%) | 43 (10.3%) | 1.09 (0.65-1.83) | | G allele | 215 (88.8%) | 373 (89.7%) | 1.00 (ref.) |
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#Adjusted the effects of age and gender. OR: odds ratio; CI: confidence interval; ref.: reference.
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