[Retracted] Effects of Ozone on Hippocampus BDNF and Fos Expressions in Rats with Chronic Compression of Dorsal Root Ganglia

Figure 1

Effect of epidural ozone injection in alleviating pain in CCD model SD rats. With CCD, the thermal withdrawal latency (TWL) and mechanical withdrawal threshold (MWT) significantly reduced from day 1 to day 21 postsurgery ( for both) ((a) and (b)). The thermosensitive pain was alleviated between day 7 and day 21 after surgery in the group ( for all except day 10, where ). The thermosensitive pain was significantly alleviated in the group between day 3 and day 21 after surgery ( for both). The thermosensitive pain-relieving effect between day 3 and day 21 postsurgery was more pronounced in the group than in the group ( for both) (a). The mechanical allodynia was alleviated between day 7 and day 21 in the group ( for all except day 7, where ). The mechanical allodynia was also relieved significantly in the group between day 5 and day 21 ( for all except day 5, where ). The thermosensitive pain-relieving between day 7 to day 21 was more pronounced in the group than in the group () (b). Data are expressed as (^a and ^aa, vs. sham group; ^b and ^bb, vs. CCD group; ^c and ^cc, vs. group).

(a)

(b)