Liver Enzymes and Their Association with Some Cardiometabolic Diseases: Evidence from a Large Kurdish Cohort

Table 4

Odds ratio (OR) and 95% CI of the MetS, HTN, and CVD (according to quartiles of liver enzymes).

Variables	Prevalence (%)	Metabolic syndrome	Prevalence (%)	Hypertension	Prevalence (%)	CVD
		Adjusted model; OR (95% CI)		Adjusted model; OR (95% CI)		Adjusted model; OR (95% CI)
ALT
Quartile 1	17.7	1.00	23.2	1.00	23.9	1.00
Quartile 2	22.1	1.17 (0.96–1.42)	26.9	0.92 (0.72–1.16)	27	0.95 (0.75–1.20)
Quartile 3	27	1.68 (1.38–2.03)	27.1	0.90 (0.70–1.15)	26.8	1.02 (0.80–1.29)
Quartile 4	33.2	2.45 (2.01–2.98)	22.8	0.91 (0.70–1.17)	22.3	1.008 (0.78–1.29)
AST
Quartile 1	24.7	1.00	24.7	1.00	26	1.00
Quartile 2	23.7	0.95 (0.79–1.13)	24.9	0.94 (0.74–1.18)	25	0.97 (0.77–1.21)
Quartile 3	24.9	1.08 (0.91–1.30)	26.3	1.02 (0.81–1.29)	26	0.96 (0.76–1.21)
Quartile 4	26.7	1.19 (1–1.43)	24.1	1.02 (0.80–1.30)	23	1.02 (0.80–1.28)
ALT/AST ratio
Quartile 1	15.9	1.00	24	1.00	24.3	1.00
Quartile 2	20.8	1.10 (0.89–1.35)	25.2	0.95 (0.74–1.22)	25.2	0.97 (0.76–1.23)
Quartile 3	28	1.78 (1.47–2.17)	26.8	1.00 (0.78–1.29)	26.5	0.98 (0.77–1.24)
Quartile 4	35.3	2.94 (2.40–3.59)	24	1.01 (0.78–1.30)	24	1.10 (0.85–1.41)
GGT
Quartile 1	13.3	1.00	18.4	1.00	19.3	1.00
Quartile 2	21.1	1.65 (1.35–2.02)	23.6	1.03 (0.79–1.34)	23.3	1.07 (0.83–1.37)
Quartile 3	30.4	2.46 (2.01–3)	27.9	1.27 (0.99–1.64)	27	1.29 (1.01–1.66)
Quartile 4	35.2	3.29 (2.70–4.02)	30.1	1.33 (1.03–1.71)	30.3	1.54 (1.20–1.98)
ALP
Quartile 1	18.7	1.00	19.1	1.00	19.6	1.00
Quartile 2	23.2	1.34 (1.10–1.62)	22.2	1.01 (0.78–1.31)	23.9	0.94 (0.73–1.21)
Quartile 3	26.3	1.52 (1.26–1.84)	23.5	0.87 (0.67–1.13)	25	0.82 (0.64–1.05)
Quartile 4	31.8	2.00 (1.66–2.41)	35.2	1.32 (1.03–1.68)	32.4	1.03 (0.81–1.31)

ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transferase; ALP: alkaline phosphatase. Adjusted model for gender, age, smoking status, physical activity, and BMI. Without adjusted models.