Optimization of Preanalytical Variables for cfDNA Processing and Detection of ctDNA in Archival Plasma Samples

Figure 5

Mutations were identified in ctDNA in three archival clinical samples with known mutations. Fractional abundance of mutations presented in percentage for gDNA assessed by WES and ddPCR and ctDNA assessed by ddPCR. The third patient was missing the relapse plasma sample, but we could detect mutation in the diagnostic plasma sample.