Interferon-Induced Transmembrane Protein 3 Expression Upregulation Is Involved in Progression of Hepatocellular Carcinoma

Figure 1

IFITM3 was overexpressed in hepatic tissues of HCC patients and was survival-associated. (a, b) Chart and plot showing the expression of IFITM3 in tumor tissues and the adjacent normal tissues in HCCDB. (c) Box plot showing IFITM3 mRNA levels in the Roessler Liver 2. (d) IFITM3 transcription in subgroups of patients with HCC (UALCAN). Immunohistochemical results of IFITM3 expression were detected in HCC tissues (e) and adjacent normal tissues (f); magnification: ×100 (). (g) IFITM3 IOD level was tested in HCC tissues and adjacent normal tissues using IPP6.0 (). IFITM3 expression levels were assessed in tumor tissues and adjacent normal hepatic tissues using qRT-PCR (h) and western blotting (i) (). (j) IFITM3 is associated with survival outcome in TCGA LIHC cohort.

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