Interferon-Induced Transmembrane Protein 3 Expression Upregulation Is Involved in Progression of Hepatocellular Carcinoma

Figure 2

IFITM3 positively regulates HCC cell proliferation and migration. (a) IFITM3 expression was evaluated by western blotting analysis in three HCC cell lines. (b–d) Examination of IFITM3 expression in stably transfected HCC cells using western blotting and qRT-PCR. , , and . (e, f) Wound healing tests were performed to detect cell migration in LV-IFITM3 and pLenti-CMV-IFITM3 HCC cells. Magnification, ×40. (g) CCK-8 assays were used to monitor cell proliferation in indicated cells. vs. normal. The data were analyzed using Student’s test, and the data are shown as the , with three independent experiments in each group.

(a)

(b)

(c)

(d)

(e)

(f)

(g)