The Association between Postoperative Cognitive Dysfunction and Cerebral Oximetry during Geriatric Orthopedic Surgery: A Randomized Controlled Study
Table 4
Regional cerebral oxygen saturation value for geriatric orthopedic surgery.
Patient characteristic
Cognitive dysfunction at baseline
Difference (95% CI)
value
Cognitive dysfunction at 3 months
Difference (95% CI)
value
No-POCD (45)
POCD (45)
No-POCD (30)
POCD (26)
Preoperative rScO2
0.8 (-2.0; 3.2)
0.053
0.8 (-2.0; 3.2)
0.625
Mean rScO2 during surgery
1.2 (-1.2; 2.3)
0.251
3.2 (-6.3; 2.3)
0.514
Time below preoperative rScO2 (min)
2.8 (-5.3; 2.6)
0.125
3.6 (-6.5; 3.1)
0.015
Time below a 10% decrease from preoperative rScO2 (min)
5.9 (-5.8; 2.6)
0.325
2.3 (-1.1; 2.0)
0.011
Time below a 20% decrease from preoperative rScO2 (min)
0.0 (-0.2; 0.1)
0.125
0.1 (-0.2; 0.3)
0.09
CDL preoperative ()
53.6 (-53.1; 26.3)
0.102
61.25 (-73.61; 56.36)
0.025
CDL10 ()
6.5 (-5.9; 6.2)
0.089
8.61 (-6.3; 7.25)
0.364
CDL20 ()
0.0 (-0.3; 0.5)
0.521
0.0 (-0.2; 0.5)
0.085
Minimum rScO2 value
2.3 (-1.2; 2.6)
0.261
3.6 (-4.5; 5.1)
0.02
Maximum rScO2 value
5.3 (-3.6; 2.3)
0.251
6.1 (-5.1; 6.1)
0.01
Regional cerebral oxygen saturation (rScO2).CDL: cerebral desaturation load (area under these thresholds). Data are presented as , or median (5th–95th percentile), or percentage of all patients. POCD: postoperative cognitive dysfunction.