Research Article

The Association between Postoperative Cognitive Dysfunction and Cerebral Oximetry during Geriatric Orthopedic Surgery: A Randomized Controlled Study

Table 4

Regional cerebral oxygen saturation value for geriatric orthopedic surgery.

Patient characteristicCognitive dysfunction at baselineDifference (95% CI) valueCognitive dysfunction at 3 monthsDifference (95% CI) value
No-POCD (45)POCD (45)No-POCD (30)POCD (26)

Preoperative rScO20.8 (-2.0; 3.2)0.0530.8 (-2.0; 3.2)0.625
Mean rScO2 during surgery1.2 (-1.2; 2.3)0.2513.2 (-6.3; 2.3)0.514
Time below preoperative rScO2 (min)2.8 (-5.3; 2.6)0.1253.6 (-6.5; 3.1)0.015
Time below a 10% decrease from preoperative rScO2 (min)5.9 (-5.8; 2.6)0.3252.3 (-1.1; 2.0)0.011
Time below a 20% decrease from preoperative rScO2 (min)0.0 (-0.2; 0.1)0.1250.1 (-0.2; 0.3)0.09
CDL preoperative ()53.6 (-53.1; 26.3)0.10261.25 (-73.61; 56.36)0.025
CDL10 ()6.5 (-5.9; 6.2)0.0898.61 (-6.3; 7.25)0.364
CDL20 ()0.0 (-0.3; 0.5)0.5210.0 (-0.2; 0.5)0.085
Minimum rScO2 value2.3 (-1.2; 2.6)0.2613.6 (-4.5; 5.1)0.02
Maximum rScO2 value5.3 (-3.6; 2.3)0.2516.1 (-5.1; 6.1)0.01

Regional cerebral oxygen saturation (rScO2).CDL: cerebral desaturation load (area under these thresholds). Data are presented as , or median (5th–95th percentile), or percentage of all patients. POCD: postoperative cognitive dysfunction.