Research Article

The Effects of Combining Cancer Drugs with Compounds Isolated from Combretum zeyheri Sond. and Combretum platypetalum Welw. ex M.A. Lawson (Combretaceae) on the Viability of Jurkat T Cells and HL-60 Cells

Figure 7

The antiproliferative effects of combining CP 404 and doxorubicin on Jurkat T cells. The antiproliferative effects of CP 404 (GI50, 1/2 GI50, 1/4 GI50, 1/8 GI50, 1/16 GI50, and 1/32 GI50), when combined with doxorubicin (0–16 μg/ml), were determined using the MTT assay to investigate the number of viable cells present in the sample. The results show that at low concentration of chlorambucil, there was no significant reduction in cell density compared to cells with cell (RPMI) media only. The cell density corresponds to the number of viable cells present in the sample. The values are (SD) of 2 replicate data sets.