Mass Spectrometry and Computer Simulation Predict the Interactions of AGPS and HNRNPK in Glioma

Table 5

SAS values of polar residues and nonpolar residues at the interface of the HNRPK-AGPS complex.

Receptor protein (HNRPK) residue	Contact surface area	Polar contact surface area	Nonpolar contact surface area	Ligand protein (AGPS) residue	Contact surface area	Polar contact surface area	Nonpolar contact surface area
GLN50	29.08	29.08	0.00	TRP93	7.20	0.00	7.20
PRO84	2.22	0.00	2.22	ASP141	1.77	1.77	0.00
LEU133	16.34	0.00	16.34	SER146	1.27	1.27	0.00
ARG148	10.07	10.07	0.00	SER149	9.55	9.55	0.00
THR177	6.84	6.84	0.00	LEU150	13.02	0.00	13.02
ILE178	0.51	0.51	0.00	ASN151	19.17	19.17	0.00
PHE181	10.25	0.00	10.25	PRO152	8.62	8.62	0.00
GLN182	19.49	19.49	0.00	PRO157	7.76	0.00	7.76
GLU183	2.49	0.00	2.00	PHE195	6.65	0.00	6.65
LEU194	20.77	0.00	492852.00	LEU196	22.71	0.00	22.71
ILE218	1.38	0.00	0.77	LEU197	4.31	4.31	0.00
PHE253	26.59	0.00	—	MET246	6.92	0.00	6.92
GLY260	8.31	0.00	384922.00	PRO248	8.86	0.00	8.86
ASP281	0.51	0.51	6.59	LEU444	23.54	0.00	23.54
LEU307	1.11	0.00	0.31	LYS448	13.78	13.78	0.00
PRO308	15.21	15.21	0.00	GLN462	5.83	5.83	0.00
MET336	12.66	0.00	1.11	TYR522	0.83	0.00	0.83
TYR361	2.03	2.03	0.00	GLY556	7.86	7.86	0.00
GLU362	1.94	0.00	12.66	VAL557	0.25	0.25	0.00
PRO363	23.82	0.00	0.00	PRO560	9.14	0.00	9.14
GLN364	7.76	0.00	1.00	PRO591	12.74	0.00	12.74
GLN445	0.76	0.76	938892.00	LEU592	16.34	0.00	16.34
			3.82	GLU596	16.22	16.22	0.00
			0.76	LYS628	3.71	3.71	0.00
			0.00	PHE636	12.19	0.00	12.19