3D-QSAR Studies of 1,2,4-Oxadiazole Derivatives as Sortase A Inhibitors

Figure 5

The visualizing of the 3D-QSAR model in the field of unfavorable and favorable effects of hydrogen bond donor (HBD) in: (a) ligand 89 and (b) ligand 120. The visualizing of the 3D-QSAR model in the field of unfavorable and favorable effects of interaction in (c) ligand 89 and (d) ligand 120. The visualizing of the 3D-QSAR model in the field of unfavorable and favorable effects of electron-withdrawing groups in (e) ligand 89 and (f) ligand 120 in two different dimensions, (positive coefficient color: dark blue, negative coefficient color: red, most active compound is 89 (), and least active compound is 120 ()).

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