Research Article
3D-QSAR Studies of 1,2,4-Oxadiazole Derivatives as Sortase A Inhibitors
Table 2
Seven factors of PLS were calculated for the QSAR model.
| # factors | H-bond donor | Hydrophobic/nonpolar | Negative ionic | Positive ionic | Electron-withdrawing |
| 1 | 0.028420 | 0.709533 | 0.030517 | 0.031581 | 0.156872 | 2 | 0.029319 | 0.646792 | 0.039072 | 0.039833 | 0.190441 | 3 | 0.028610 | 0.647774 | 0.045189 | 0.045139 | 0.200709 | 4 | 0.029662 | 0.668252 | 0.038533 | 0.037152 | 0.195964 | 5 | 0.029213 | 0.666539 | 0.039458 | 0.037827 | 0.195301 | 6 | 0.029931 | 0.669972 | 0.037575 | 0.035876 | 0.194004 | 7 | 0.032992 | 0.677689 | 0.033050 | 0.032073 | 0.191071 |
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