Research Article

Evaluation of Acute and Subchronic Toxicity Induced by the Crude Ethanol Extract of Plukenetia volubilis Linneo Leaves in Swiss Albino Mice

Table 1

The effect of EtPV on the food intake, water consumption, and body weight of mice by acute and subchronic toxicity assays.

GroupAverage food intake (g/day)Average water intake (ml/day)Body weight
Actual weight (g)Weight gain (%)

Acute oral toxicity
 Control group
  1000 mg/kg
  3000 mg/kg
  5000 mg/kg
  7000 mg/kg
Subchronic oral toxicity
 Control group
  100 mg/kg
  300 mg/kg
  500 mg/kg
  700 mg/kg

Values are displayed as . Value that is significantly different from the corresponding value of the control group () was marked with an asterisk.