Research Article

Evaluation of Acute and Subchronic Toxicity Induced by the Crude Ethanol Extract of Plukenetia volubilis Linneo Leaves in Swiss Albino Mice

Table 2

The effect of EtPV on the hematological parameters in mice by acute and subchronic toxicity assays.

GroupRBC (×106cell/mm3)HGB (g/dl)PLT (×103cell/mm3)WBC (×103cell/mm3)Lymphocyte (%)Monocyte (%)Granulocytes (%)

Acute oral toxicity
 Control group
  1000 mg/kg
  3000 mg/kg
  5000 mg/kg
  7000 mg/kg51.83 ± 1.58
Subchronic oral toxicity
 Control group
  100 mg/kg
  300 mg/kg
  500 mg/kg
  700 mg/kg

Values are displayed as . Value that is significantly different from the corresponding value of the control group () was marked with an asterisk.