Evaluation of Acute and Subchronic Toxicity Induced by the Crude Ethanol Extract of Plukenetia volubilis Linneo Leaves in Swiss Albino Mice

Table 4

The effect of EtPV on the relative organ weight of the heart, liver, and kidney in mice measured by acute and subchronic toxicity assays.

Group	Heart weight		Liver weight		Kidney weight
	M (g)	ROW (%)	M (g)	ROW (%)	M (g)	ROW (%)
Acute oral toxicity
Control group
1000 mg/kg
3000 mg/kg
5000 mg/kg
7000 mg/kg
Subchronic oral toxicity
Control group
100 mg/kg
300 mg/kg	0.24 ± 0.03	0.86 ± 0.03	1.33 ± 0.11	4.79 ± 0.36	0.31 ± 0.03	1.16 ± 0.08
500 mg/kg
700 mg/kg			1

Values are displayed as . Value that is significantly different from the corresponding value of the control group () was marked with an asterisk.