Research Article

[Retracted] Improvement of Cerebral Ischemia-Reperfusion Injury via Regulation of Apoptosis by Exosomes Derived from BDNF-Overexpressing HEK293

Figure 2

Comparing the treatment effects of exosomes to control HEK293 cells (EXO) or BDNF-overexpressing HEK293 cells (EXO-BDNF) against H/R cell model prompted SY-5Y cell damage. (a) Assessment of the apoptotic process of SY-5Y cells by incorporating flow cytometry accompanied by staining by Annexin V-FITC and PI. (b) The bar chart showed the relative apoptosis rate analyzed three times. (c) Demonstration of caspase-3 detected by Western blot. (d) Relative levels of protein of caspase-3 showed by the bar chart. Values represent the mean of the 3 individual investigations (, , ). H/R (model group): hypoxia/reoxygenation cell model.
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