Total Saponins from <i>Nigella glandulifera</i> Seeds Ameliorate Adjuvant-Induced Rheumatoid Arthritis in Rats by Inhibition of an Inflammatory Response and Bone Erosion

<div>Analysis of the UHPLC-HRMS chromatogram of TSNGS. The chemical composition of TSNGS was confirmed by UHPLC-HRMS based on retention time and fragmentation behavior, in addition to accurate mass measurement and characteristic fragmentation. A total of 21 compounds were identified, including triterpene saponins, alkaloids, flavonoid glycosides, and phenolic compounds. (a) UHPLC-Q-Orbitrap-HRMS chromatogram of TSNGS. UHPLC-PDA chromatogram of TSNGS at the wavelengths: (b) 210 nm, (c) 254 nm, (d) 330 nm, and (e) 365 nm.</div>

BioMed Research International

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Figure 1

Figure 1: Total Saponins from <i>Nigella glandulifera</i> Seeds Ameliorate Adjuvant-Induced Rheumatoid Arthritis in Rats by Inhibition of an Inflammatory Response and Bone Erosion 

Figure 1 | Total Saponins from Nigella glandulifera Seeds Ameliorate Adjuvant-Induced Rheumatoid Arthritis in Rats by Inhibition of an Inflammatory Response and Bone Erosion 