Total Saponins from Nigella glandulifera Seeds Ameliorate Adjuvant-Induced Rheumatoid Arthritis in Rats by Inhibition of an Inflammatory Response and Bone Erosion

Figure 6

TSNGS decreased bone erosion by increasing the OPG/RANKL ratio in AIA rats. Levels of OPG (a) and RANKL (b) in rat serum were measured using ELISA. (c) Ratio of OPG/RANKL expression in rat serum. (d) Representative images of OPG and RANKL in the various groups. (e) Quantitative WB analysis. Results represent . , ^#, ^##, ^### vs. sham, , , vs. model.

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