Research Article

Total Saponins from Nigella glandulifera Seeds Ameliorate Adjuvant-Induced Rheumatoid Arthritis in Rats by Inhibition of an Inflammatory Response and Bone Erosion

Figure 7

The potential mechanism by which TSNGS alleviates the pathological process of RA. TSNGS affected the inflammatory response by regulating anti-inflammatory and proinflammatory cytokines and suppressed bone erosion by activation of the OPG/RANKL pathway.