[Retracted] CD4-Targeted T Cells Rapidly Induce Remissions in Mice with T Cell Lymphoma

<div>CD4-CAR-T cells exhibited potent cytotoxic activity in vitro. The cytotoxic activity of CD4-CAR-T cells was determined by coculture of CD4-CAR-T cells or control T cells (effector cells, E) with T1301 tumor cells, a T-ALL cell lines (target cells, T) at different E : T ratio. CD4+ and CD8+ T cells were analyzed 24 hours after coculture by flow cytometry analysis. (a) Representative plot was shown for each treatment. (b) Quantitative analysis of cytotoxic activity of CD4-CAR-T cells at different E : T ratio. 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d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g></svg>,</span> vs. T cell group.</div>

BioMed Research International

fig3

Figure 3

Figure 3: [Retracted] CD4-Targeted T Cells Rapidly Induce Remissions in Mice with T Cell Lymphoma 