[Retracted] MicroRNA-4325 Suppresses Cell Progression in Hepatocellular Carcinoma via GATA-Binding Protein 6

Figure 4

miR-4325 suppresses HCC cell migration and invasion through targeting GATA6. GATA6 was successfully overexpressed or knocked down in Li-7 (a) and HuH-7 (b) cell lines. (c, d) HCC cell lines expressed a higher level of GATA6 than THLE-2 cell line. (e) Western blot analysis of GATA6 expression levels. Comparisons of miR-4325 relative expression levels between miR-4325 mimics and KDGATA6 (f) or between miR-4325 mimics and OEGATA6 (g). Detection of migrating ability of cells transfected with miR-4325 mimics and KDGATA6 (h) or with miR-4325 mimics and OEGATA6 (i). Detection of invasion ability of cells transfected with miR-4325 mimics and KDGATA6 (j) or with miR-4325 mimics and OEGATA6 (k). (l) Images of migration and invasion assay in Li-7 cells (scale bar: 100 μm). vs. control+KDCON or control+OECON. ^# vs. control+KDGATA6 or control+OEGATA6. KDCON: knockdown control; OECON: overexpression control.

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