Research Article

A Comparative Study of the Effects of Valproate and Oxcarbazepine on Sexual Function, Sperm Quality, and Sex Hormones in Males with Epilepsy

Table 2

Comparison of semen quality, IIEF-5 questionnaire scores, and sex hormone levels between the epilepsy group and the control group.

Epilepsy groupControl group

Sperm concentration (×106/mL)0.005
Total number of sperm (×106/ejaculation)0.004
Sperm percentage with forward movementNS
Normal sperm percentageNS
IIEF-5 questionnaire score (points)a0.001
PRL level (mIU/L)NS
FSH level (mIU/mL)NS
LH level (mIU/mL)NS
T level (nmol/L)NS
E2 level (pmol/L)NS

aThe results were obtained from 38 sexually active epilepsy patients and 28 healthy volunteers who had sex.