A Comparative Study of the Effects of Valproate and Oxcarbazepine on Sexual Function, Sperm Quality, and Sex Hormones in Males with Epilepsy

Table 4

Comparison of semen quality, sexual function questionnaire scores, and sex hormone levels in the VPA group before and after treatment for 6 months.

	Before medication	After medication
Sperm concentration (×10^6/mL)			0.003
Total number of sperm (×10^6/ejaculation)			0.012
Sperm percentage with forward movement			0.001
Normal sperm percentage			NS
IIEF-5 questionnaire score (points)^a			NS
PRL level (mIU/L)			0.029
FSH level (mIU/mL)			NS
LH level (mIU/mL)			NS
T level (nmol/L)			NS
E2 level (pmol/L)			NS

^aThe results were obtained from 20 epilepsy patients who had sex.