Research Article

Effect of Intravenous Lidocaine on Inflammatory and Apoptotic Response of Ischemia-Reperfusion Injury in Pigs Undergoing Lung Resection Surgery

Table 2

Histopathological assessment of inflammation in ischemia-reperfusion lung injury by hematoxylin-eosin staining. Samples were collected 60 minutes after reperfusion.

GroupDegreeInflammation (, #)Infiltration
MM (, #)LymphocytesNeutrophils

CONAbsence116.7%116.7%233.3%6100%
Scarce466.7%583.3%350%00%
Moderate116.7%00%116.7%00%
Abundant00%00%00%00%

LIDOAbsence583.3%583.3%583.3%6100%
Scarce116.7%116.7%116.7%00%
Moderate00%00%00%00%
Abundant00%00%00%00%

SHAMAbsence583.3%6100%583.3%6100%
Scarce116.7%00%116.7%00%
Moderate00%00%00%00%
Abundant00%00%00%00%

MM: monocyte-macrophage system; : number of cases in the group; : percentage of cases in the group; CON: control group; LIDO: group treated with lidocaine; SHAM: simulated surgery group. SHAM vs. CON; #LIDO vs. CON.