Quercetin Alleviates Intervertebral Disc Degeneration by Modulating p38 MAPK-Mediated Autophagy

<div>The effects of QUE and TBHP on NPC viability. (a) Growth curves of NPCs during the first 72 h of culture. (b, c) Viability of NPCs treated with different concentrations of QUE and TBHP for 24 h. (d) Viability of TBHP-induced NPCs pretreated with QUE. (e) Representative images showing morphological changes in NPCs after pretreatment with different concentrations of QUE followed by incubation with 50 <i>μ</i>M TBHP (original magnification ×200, scale bar: 50 <i>μ</i>m). 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BioMed Research International

fig1

Figure 1

Figure 1: Quercetin Alleviates Intervertebral Disc Degeneration by Modulating p38 MAPK-Mediated Autophagy 