Transfer of Th17 from Adult Spontaneous Hypertensive Rats Accelerates Development of Hypertension in Juvenile Spontaneous Hypertensive Rats

Figure 3

Accelerated development of hypertension in juvenile SHR by transfer of adult Th17 cells. (a) Schematic illustration shows that Th17 cells from adult donor SHR or the vehicle was transferred into juvenile recipient WKY or SHR. Intraperitoneal injections with Th17 cells from adult SHR or the vehicle were administrated into juvenile recipient WKY or SHR. SBP was measured in juvenile recipient (b) WKY and (c) SHR for 4 days using the tail-cuff method. The transfer of Th17 cells from adult SHR into juvenile recipient SHR significantly increased SBP than the vehicle group, which was not seen in juvenile recipient WKY. Data are the of 6 independent experiments ( vs. vehicle group by repeated measures ANOVA).

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