The Combination of Shear Wave Elastography and Platelet Counts Can Effectively Predict High-Risk Varices in Patients with Hepatitis B-Related Cirrhosis

Table 2

Diagnostic accuracy of 2D-SWE to discriminate all size varices and high-risk varices in patients with hepatitis B-related cirrhosis.

Patients with hepatitis B-related cirrhosis ()
Diagnostic indexes	All size varices	High-risk varices
AUC (95% CI)	0.834 (0.767-0.888)	0.881 (0.820-0.927)
^‡Cut-off values	11.4 kPa	14.50 kPa
Sensitivity	0.77 (0.61-0.88)	0.77 (0.56-0.91)
Specificity	0.80 (0.72-0.87)	0.91 (0.85-0.95)
PPV	0.59 (0.45-0.72)	0.63 (0.44-0.79)
NPV	0.90 (0.83-0.95)	0.95 (0.90-0.98)
Positive LR	3.9 (2.6-5.8)	8.6 (4.8-15.3)
Negative LR	0.3 (0.2-0.5)	0.3 (0.1-0.5)

Note: data in parentheses are 95% confidence intervals. ^‡A cut-off was set to maximize the sum of sensitivity and specificity. Abbreviations: PPV: positive predictive value; NPV: negative predictive value; LR: likelihood ratio; CI: confidence interval.