Whether Intracranial Aneurysm Could Be Well Treated by Flow Diversion: A Comprehensive Meta-Analysis of Large-Sample Studies including Anterior and Posterior Circulation
Table 3
Occlusion data from angiographic follow-up.
of CO
of followed
Rate, 95% CI
value of
Totala
4491
5715
0.78 (0.75, 0.82)
90.6%
<0.001
Angiographic follow-up
520
763
0.68 (0.65, 0.72)
0.0%
0.576
AFU at 6 months
2996
3828
0.78 (0.77, 0.80)
9.7%
0.341
AFU 6~12 months
1389
1554
0.90 (0.88, 0.92)
34.4%
0.133
Subgroup analysis of AFU at 6 months
FD
PED
2486
3187
0.78 (0.77, 0.80)
0.0%
0.921
Other FD
510
641
0.79 (0.72, 0.86)
78.4%
0.010
Age (year)
>55
442
572
0.78 (0.77, 0.80)
28.3%
0.160
<55
2554
3256
0.77 (0.74, 0.81)
0.0%
0.937
Dome (mm)
<10
2016
2567
0.79 (0.77, 0.80)
0.0%
0.971
>10
508
677
0.75 (0.72, 0.78)
0.0%
0.779
Center
Single
160
210
0.76 (0.70, 0.82)
—
—
Multi
2836
3618
0.79 (0.77, 0.80)
12.0%
0.316
aTotal outcome of studies with the maximum AFU number. Significant heterogeneity. Abbreviations: AFU: angiographic follow-up; CO: complete occlusion; FD: flow diversion; PED: pipeline embolization device; 95% CI: 95% confidence interval.
