Development of the Binary and Ternary Atorvastatin Solid Dispersions: In Vitro and In Vivo Investigations

Figure 1

Dissolution profiles of untreated drug (ATR), binary solid dispersion (BS), ternary solid dispersion (TS), and relevant physical mixture (PM) with different drug : carrier ratios: (a) ATR : PEG 4000, (b) ATR : PEG 10000, (c) ATR : poloxamer 188, and (d) ATR : poloxamer 188 : PEG 10000 ().

(a)

(b)

(c)

(d)