Association of Matrix Metalloproteinase-2 mRNA Expression with Subtypes of Pediatric Cholesteatoma

Figure 3

RNA-in situ hybridization assay in pediatric cholesteatoma, probing for MMP2. (a) A minute number of MMP2-positive signals were observed in congenital cholesteatoma (closed type). (b–d) MMP2-positive signals were observed in inflammatory cells in the stroma of congenital cholesteatoma (open type), pars flaccida type, and pars tensa type of acquired cholesteatoma. The MMP2 signal is shown as brown puncta.

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