Correlationship between Ki67, VEGF, and p53 and Hepatocellular Carcinoma Recurrence in Liver Transplant Patients

Table 1

Correlation between the expression of Ki67, VEGF, and p53 and clinicopathological characteristics of HCC patients.

Clinicopathological characteristics		Ki67 expression			VEGF expression			p53 expression
		-	+		-	+		-	+
Gender				1.000			1.000			0.238
	Male	25	32		30	27		29	28
	Female	2	1		2	1		0	3
Age				0.388			0.088			1.000
	≦60	22	32		31	23		26	28
	>60	4	2		1	5		3	3
Child-Pugh class				1.000			0.883			0.494
	A	8	11		10	9		8	11
	B	18	12		22	18		21	19
	C	0	1		0	1		0	1
Tumor size				0.203^†			0.037^†			0.044^†
	≦5.0	16	15		21	10		19	12
	>5.0	10	19		11	18		10	19
Tumor number				0.005^†			0.005^†			0.617^†
	1	19	12		11	20		16	15
	≧2	7	22		21	8		13	16
AFP				0.174^†			1.000^†			0.419^†
	>400	6	14		11	9		8	12
	≦400	20	20		21	19		21	19
TNM staging				0.122			0.659			0.857
	I	4	2		4	2		3	3
	II	11	9		12	8		4	11
	III	6	3		3	6		9	5
	IV	5	20		13	12		13	12
Vascular invasion				0.398			0.783^†			0.544^†
	Yes	4	14		6	12		7	11
	No	22	20		26	16		22	20
Cirrhosis				0.072			0.379^†			0.082
	Yes	23	23		23	23		25	21
	No	3	11		9	5		4	10
Tumor encapsulation				0.416^†			0.578^†			0.022
	Yes	21	21		24	19		25	18
	No	5	12		8	9		4	13
Lymphatic metastasis				1.000			0.025			0.750
	Yes	1	1		0	2		0	2
	No	25	33		32	26		29	29
Differentiation				0.038			0.035			0.081
	Low	1	10		2	9		2	9
	Medium	19	18		22	15		21	37
	High	6	6		8	4		6	12

: Fisher test; †: Pearson chi-square test; “+”: positive; “-”: negative.