Glial Cell-Derived Neurotrophic Factor Functions as a Potential Candidate Gene in Obstructive Sleep Apnea Based on a Combination of Bioinformatics and Targeted Capture Sequencing Analyses

Table 3

Baseline characteristics of subjects for targeted sequencing.

Variables	Non-OSA ()	Severe OSA ()	value
Gender (male, %)	29 (58.0%)	40 (80.0%)	0.017
Age (years)			0.006
Body mass index (kg/m^2)	24.96 (22.96, 26.66)	30.06 (27.45, 31.68)	<0.001
Neck circumference (cm)			<0.001
Abdomen circumference (cm)			<0.001
Alcohol history (, %)	14 (28.0%)	7 (14.0%)	0.086
Systolic blood pressure (mmHg)			0.748
Diastolic blood pressure (mmHg)			0.389
Apnea hypopnea index (events/h)	0.80 (0.40, 2.13)	59.05 (53.85, 70.60)	<0.001
Apnea index (events/h)	0.00 (0.00, 0.30)	43.25 (32.45, 57.90)	<0.001
Hypopnea index (events/h)	0.75 (0.38, 1.90)	14.75 (9.65, 27.70)	<0.001
Lowest oxyhemoglobin saturation (%)	89.0 (87.0, 91.0)	68.0 (61.0, 74.0)	<0.001
Mean arterial oxygen saturation (%)	94.00 (93.00, 95.25)	91.00 (88.75, 92.00)	<0.001
Sleep efficiency (%)	68.20 (63.20, 74.75)	72.35 (61.10, 78.18)	0.329
Total sleep time (min)	413.25 (379.00, 449.13)	421.50 (387.38, 453.38)	0.608