Upregulation of miR-138 Increases Sensitivity to Cisplatin in Hepatocellular Carcinoma by Regulating EZH2

Figure 6

EMT is involved in miR-138 and EZH2-mediated regulation of sensitivity to cis. (a) CCK-8 assay analyzed cell viability of different groups (NC mimic, miR-138 mimic, NC mimic+cis, miR-138 mimic+cis, miR-138 mimic+EZH2 plasmid+cis). (b) Western blotting was determined to analyze E-cadherin and vimentin expression in the different groups (NC mimic, miR-138 mimic, NC mimic+cis, miR-138 mimic+cis, miR-138 mimic+EZH2 plasmid+cis).

(a)

(b)