MicroRNA-27a Promotes Oxidative-Induced RPE Cell Death through Targeting FOXO1

Figure 1

Functional and histological assessment of the RD rat model. (a) Representative ERG response graph of the control group and RD model group at the indicated times. All ERG waves gradually decreased with time. (b) ERG amplitudes of the a-waves and b-waves. (c) Representative H&E staining of retinal sections from the control group and RD rat model group at the indicated time points. There is an obvious disorder of retinal structure and a decrease of retinal thickness over time ( μM). (d) Statistical analysis of the ONL thickness in the above groups (superior to inferior from the optic nerve head). The data are calculated as . , , and , comparisons versus control, (eye samples in each group).

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