Review Article
A Systematic Review and Meta-Analysis of Combined Antibiotic Spacer with Ilizarov Methods in the Treatment of Infected Nonunion of Tibia
Table 2
Characteristics of included studies.
| | Study no. | First author | Year | Study design | Number of patients | Men/women | Age (years) | Mean previous operations (per patient) | Mean bone defects (cm) | Mean time from initial treatment (months) | Follow-up (months) |
| | 1 | Wang [24] | 2019 | RC | 31 | 18/13 | 44.68 | 7.5 | — | 7.48 | — | | 2 | Li [23] | 2019 | RS | 18 | 11/7 | 41.2 | 18 | 11.8 | 11.1 | 21.5 | | 3 | Xue [22] | 2018 | RS | 12 | 9/3 | 31.5 | — | 10 | — | 14.5 | | 4 | Zhang [14] | 2017 | RC | 8 | — | 41.3 | 3.1 | 6.4 | 22.8 | 31 | | 5 | Ren [20] | 2017 | RS | 14 | 12/2 | 40.4 | 3.3 | 8.5 | 15.3 | 17.5 | | 6 | van Niekerk [21] | 2017 | RC | 12 | — | 35.1 | — | 5.0 | — | — | | 7 | Hou [17] | 2015 | RC | 15 | 15/0 | 31.28 | — | 4 | 10.29 | — | | 8 | Jing [19] | 2015 | RS | 58 | 38/20 | 29.4 | 6.3 | 9.5 | 30.5 | 31.6 | | 9 | Leonard [18] | 2015 | RS | 7 | — | 29 | — | 7 | 3 | 28 | | 10 | Spiegl [16] | 2013 | PS | 25 | 22/3 | 46 | — | 5.3 | 9.6 | 29.4 | | 11 | McHale [15] | 2004 | RS | 10 | 8/2 | 31 | — | — | — | 36 |
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Abbreviations: RS: retrospective case series; RC: retrospective comparative study; PS: prospective case series.
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