Safety Evaluation of Standardized Extract of Curcuma longa (NR-INF-02): A 90-Day Subchronic Oral Toxicity Study in Rats

Table 2

Group mean feed consumption (g/day/animal) of female rats administered with NR-INF-02 daily for 90 days.

Weeks	Control and control recovery	250 mg/kg		500 mg/kg		1000 mg/kg and 1000 mg/kg recovery
	Average	Average	% of control	Average	% of control	Average	% of control
1	16.48	16.17	98	16.52	100	16.75	102
2	17.13	17.05	100	17.11	100	16.925	99
3	16.94	16.93	100	17.03	101	16.865	100
4	16.69	15.67	94	16.56	99	16.43	98
5	17.11	16.46	96	17.27	101	17.135	100
6	17.36	16.67	96	17.28	100	17.4	100
7	17.37	16.51	95	17.21	99	16.815	97
8	17.17	17.21	100	17.26	101	17.03	99
9	17.40	16.89	97	17.84	103	17.17	99
10	16.52	16.32	99	16.37	99	16.155	98
11	16.93	16.2	96	16.85	100	16.615	98
12	16.54	15.36	93	16.6	100	16.005	97
13	16.04	15.16	95	14.4	90	15.07	94
14	15.74	—	—	—	—	15.91	101
15	16.43	—	—	—	—	16.86	103
16	15.83	—	—	—	—	16.16	102
17	16.30	—	—	—	—	16.43	101
Study average	16.90	16.35	96.78	16.79	99.34	16.64	98.49
Recovery average	16.08					16.34	101.64