Research Article

Purinergic Signaling Mediates PTH and Fluid Flow-Induced Osteoblast Proliferation

Figure 5

ATP and P2Y2 purinergic receptors are involved in PTH and fluid flow-induced osteoblast proliferation. Removal of ATP by apyrase or knockdown of P2Y2 receptors inhibited PTH and fluid flow-induced cell proliferation. (, , each bar represents the ).