Reduced Insulin-Like Growth Factor 1 Is Associated with Insulin Resistance in Obese Prepubertal Boys

Table 1

Clinical characteristics in the two groups according to WBISI levels.

Variable	()	()	value
Family economic status			0.350^#
≤¥5000/monthly	8/35	11/35
¥5001 ~ ¥10,000/monthly	18/35	12/35
≥¥10,001/monthly	9/35	12/35
Maternal education			0.668^#
<college	6/35	6/35
≥college	17/35	17/35
≥graduate	12/35	12/35
Paternal education			1^#
<college	8/35	11/35
≥college	12/35	12/35
≥graduate	15/35	12/35
Age (yr)			0.291
FPG	11/35	5/35	0.077^#
IGT	7/35	3/35	0.153^#
MS	18/35	16/35	0.406^#
BMI SDS			0.298
SBP (mmHg)			0.961
DBP (mmHg)			0.236
IGF-1 SDS			0.021
FT3 (pmmol/L)			0.151
FT4 (pmmol/L)	16.20 (14.67-17.34)	14.69 (12.24-16.72)	0.068
TSH (μU/mL)	2.94 (1.87-3.42)	3.79 (2.02-5.40)	0.076^#
ACTH (mmol/L)	31.85 (17.47-49.24)	22.80 (16.46-39.29)	0.144^#
COR (pg/mL)	330.00 (264.30-534.00)	360.00 (241.00-453.00)	0.539
TC (mmol/L)	4.31 (3.77-4.68)	4.16 (3.56-4.67)	0.156
HDL-C (mmol/L)			0.850
LDL-C (mmol/L)	2.64 (2.26-2.99)	2.51 (16.46-39.29)	0.162
TG (mmol/L)	1.39 (0.89-2.22)	1.30 (0.85-1.75)	0.557
Uric acid (μmol/L)			0.531
Insulin (μIU/mL)	52.17 (39.20-60.70)	17.40 (14.10-26.36)	<0.001
FBG (mmol/L)			0.078
Glucose 120 min (mmol/L)	6.97 (6.48-7.37)	6.11 (5.35-6.92)	<0.001^#
Insulin 120 min (μIU/mL)	273.80 (193.90-475.90)	56.96 (20.91-136.10)	<0.001
HOMA-IR	12.12 (8.12-14.06)	3.87 (3.12-6.05)	<0.001
HOMA-beta	673.00 (431.02-865.53)	252.79 (174.67-355.05)	<0.001
HbA1c (%)	5.90 (5.70-6.30)	5.80 (5.50-6.00)	0.473
IGI	4.26 (3.01-6.37)	2.12 (1.38-3.28)	<0.001
CRP	3.12 (1.07-4.61)	2.92 (1.14-5.68)	0.933

^#Chi-square test or Mann-Whitney test; .