Low REST Expression Indicates a Biomarker of Poor Prognosis in Patients with Renal Cell Carcinoma

Table 3

Univariate and multivariate analysis of over survival in patients with KIRC.

	Univariate analysis			Multivariate analysis
	Hazard ratio	CI95	value	Hazard ratio	CI95	value
Age	1.89	1.30-2.75	0.001	1.53	1.03-2.26	0.033
Gender	1.04	0.75-1.43	0.826
Histologic grade	2.06	1.71-2.47	0.0001	1.56	1.25-1.94	0.0001
Pathologic stage	1.96	1.71-2.24	0.0001	2.04	1.40-2.97	0.0001
M classification	2.47	1.94-3.19	0.0001	0.82	0.50-1.35	0.431
N classification	0.86	10.7-1.01	0.063
T classification	2.07	1.74-2.46	0.0001	0.80	0.55-1.18	0.260
REST	1.30	1.15-1.46	0.0001	1.20	1.04-1.39	0.010