Antitumor Effect of Inula viscosa Extracts on DMBA-Induced Skin Carcinoma Are Mediated by Proteasome Inhibition

Table 3

Interactions of the proposed compounds with the β₅ receptor.

Compounds	Residues
Tomentosin	Arg(70),Leu(66),Asn(63),Tyr(67),Phe(83),Leu(75),Val(64),Ala(79)
Inuviscolide	Glu(151),Asp(154),Leu(147),Leu(155),Gly(142),Arg(141),Val(138),Arg(154)
Isocosticacid	Glu(117),Asp(115),Tyr(113),Tyr(136),Ile(121),Phe(126),Val(128),Ser(127),Gly(129)
Carfilzomib	Gly(47),Gly(98),Ala(46),Val(128),Tyr(113),Ile(121),Phe(126),Ser(132),Ser(127,Gly(129),Tyr(136),Val(133)