Research Article

Allanblackia floribunda Seed Extract Attenuates the Ethanol-Induced Gastric Ulcer in Rats via the Inhibition of TNF-α and INF-γ Levels and Modulation in the Expression of Ki67 Protein

Table 4

Average ulcer index, and percentage (%) protection, gastric pH, and Estimated mean gray area of aqueous seed extract of Allanblackia floribunda (30, 100, and 300 mg/kg) or omeprazole in the ethanol-induced ulcer.

TreatmentUlcer indexAverage protection (%)Average pHEst. mean gray area#

Naïve control (10 mL/kg saline)
Alcohol+10 mL/kg saline
Alcohol+30 mg/kg AFE46.15
Alcohol+100 mg/kg AFE57.69
Alcohol+300 mg/kg AFE65.38
Alcohol+10 mg/kg omeprazole69.23

Data has been presented as group . The symbols , , or denote , , or , respectively, compared to the negative control (one-way ANOVA followed by Dunnett’s multiple comparison test). #Estimated mean gray of the Ki67 activity.