RBM23 Drives Hepatocellular Carcinoma by Activating NF-κB Signaling Pathway

Figure 4

In vivo RBM23 promotes angiogenesis in cancer. (a) IHC staining indicating higher p-p65 protein expression in HCC tissues than in normal liver tissues. The expression showed a high positive correlation with RBM23 (1 cm represents 100 μm). (b) RBM23 overexpression promoted the growth of tumor xenografts in nude mice. The left panel shows the photographs of the nude mouse. The right panel shows the weight of tumors after 28 days. (c) Immunohistochemistry (IHC) staining assays of the tumor microvessel density (indicated by CD31-positive cells) from subcutaneous tumors between different groups (1 cm represents 100 μm).

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