Research Article
Pharmacokinetic Study of Safrole and Methyl Eugenol after Oral Administration of the Essential Oil Extracts of Asarum in Rats by GC-MS
Table 2
Precision and accuracy of 2 analytes in rat plasma (
).
| | Compounds | Spiked concentration (ng/mL) | Intraday | Interday | | Measured concentration (ng/mL) | Accuracy (RE, %) | Precision (RSD, %) | Measured concentration (ng/mL) | Accuracy (RE, %) | Precision (RSD, %) |
| | Safrole | 120 | | 9.2 | 7.6 | | 11.4 | 6.1 | | 1200 | | 8.5 | 1.1 | | 10.8 | 2.2 | | 12000 | | 5.5 | 0.7 | | 6.4 | 1.5 | | Methyl eugenol | 80 | | 8.2 | 9.8 | | -5.5 | 8.0 | | 800 | | -6.8 | 1.9 | | -7.2 | 1.9 | | 8000 | | -7.9 | 0.6 | | -6.3 | 2.3 |
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