Research Article

Pharmacokinetic Study of Safrole and Methyl Eugenol after Oral Administration of the Essential Oil Extracts of Asarum in Rats by GC-MS

Table 4

Stability of 2 analytes in rat plasma ().

CompoundsSpiked concentration (ng/mL)Room temperature for 4 hThree freeze-thaw cyclesAuto-sampler for 12 h-80°C for 7 days
Measured concentration (ng/mL)RSD (%)Measured concentration (ng/mL)RSD (%)Measured concentration (ng/mL)RSD (%)Measured concentration (ng/mL)RSD (%)

Safrole1209.37.88.78.2
12001.21.60.33.1
120000.32.71.80.8
Methyl eugenol809.98.28.26.5
8001.02.30.85.4
80000.97.23.28.7