[Retracted] Protein Arginine Methyltransferase 5 Promotes the Migration of AML Cells by Regulating the Expression of Leukocyte Immunoglobulin-Like Receptor B4

Figure 7

mTOR pathway inhibitor attenuated the migration, invasion, and adhesion of AML cells. (a) After treatment of mTOR pathway inhibitor in MV-4-11 cells for 12 h, the numbers of cell migration in the CON group and inhibitor group were detected by Transwell migration assay. (b) Quantification analysis (a) indicated that the number of cells in the inhibitor group was significantly less than that in the CON group. (c) After treatment of mTOR pathway inhibitor in MV-4-11 cells for 12 h, the numbers of cell invasion in the CON group and inhibitor group were detected by Transwell invasion assay. (d) Quantification analysis (c) indicated that the number of invasion cells in the inhibitor group was significantly less than that in the CON group. (e) After treatment of mTOR pathway inhibitor in MV-4-11 cells for 12 h, the cell adhesion was detected, and the number of adherent cells in the inhibitor group was found to be significantly less than that in the CON group. After treatment of mTOR pathway inhibitor in THP-1 for 12 h, the (f, g) migration, (h, i) invasion, and (j) adhesion of THP-1 cells were detected. The above indexes in the inhibitor group were significantly lower than those in the CON group. All the experiments were repeated by three times. Data are expressed by (; ; ). The representative images are under 100x magnification.

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