Research Article
[Retracted] Protein Arginine Methyltransferase 5 Promotes the Migration of AML Cells by Regulating the Expression of Leukocyte Immunoglobulin-Like Receptor B4
Figure 9
The effect of inhibition of mTOR pathway on the expression of related genes in AML cells. (a) After treatment of MV-4-11 and THP-1 cells with mTOR pathway inhibitor for 12 h, the expression levels of PRMT5, p/T-mTOR, and LILRB4 in the CON group, si-CN group, si-PRMT5, and mTOR inhibitor-3 group were detected by Western blot. (b) J image grayscale analysis (a) revealed that PRMT5 had no obvious downward trend, but the expression of p-mTOR and LILRB4 was significantly decreased, and the expression of PRMT5, p-mTOR, and LILRB4 was significantly decreased in the si-PRMT5 group. β-Actin was used as the loading control. The same experiments and similar results were reproduced on THP-1 cells, as shown in (c, d). Data are expressed by (; ).
| (a) |
| (b) |
| (c) |
| (d) |