Impact of Permissive Hypoxia and Hyperoxia Avoidance on Clinical Outcomes in Septic Patients Receiving Mechanical Ventilation: A Retrospective Single-Center Study
Table 3
Patient outcomes in the prechange and postchange groups ().
Variables
Prechange group ()
Postchange group ()
value
PIP (IQR) (cmH2O)
Just after tracheal intubation
25.0 (20.0-27.0)
20.0 (20.0-25.0)
<0.001
Max PIP within 48 hours
25.0 (25.0-30.0)
23.0 (20.0-25.0)
<0.001
Plateau pressure (IQR) (cmH2O)
Just after tracheal intubation
23.0 (14.0-24.0)
16.0 (11.0-23.0)
<0.001
At max PIP within 48 hours
23.0 (23.0-28.0)
19.0 (13.0-24.0)
<0.001
P/F ratio (IQR)
Just before tracheal intubation
154.0 (89.2-279.9)
183.3 (91.0-369.4)
0.19
Just after tracheal intubation
227.0 (153.0-313.9)
237.0 (149.5-349.2)
0.58
At max PIP within 48 hours
250.0 (158.3-385.4)
243.3 (148.4-340.0)
0.38
Barotrauma (%)
12.0
11.5
0.91
Duration of MV (IQR) (days)
11.0 (6.0-19.0)
7.0 (3.0-14.0)
0.01
ICU stay (IQR) (days)
11.0 (6.0-19.0)
9.0 (4.0-15.0)
0.02
Hospital stay (IQR) (days)
40.0 (24.0-69.0)
44.0 (22.0-73.0)
0.77
ICU mortality (%)
31.3
23.1
0.18
In-hospital mortality (%)
44.6
44.6
1.00
Values are presented as median (IQR) for continuous variables and percentage for categorical variables. Abbreviations: PIP: peak inspiratory pressure; IQR: interquartile range; P/F: partial pressure of arterial oxygen/fraction of inspiratory oxygen; MV: mechanical ventilation.
