Osteosarcoma Cell-Derived Exosomal miR-1307 Promotes Tumorgenesis via Targeting AGAP1

<div>Effects of OS-Exos on proliferation, migration and invasion of OS cells after downregulating miR-1307 in OS-Exos. (a, b) The mRNA levels of miR-1307 in OS-Exos after OS cells transfected with miR-NC inhibitor or miR-1307 inhibitor were assayed by qRT-PCR. (c, d) Effects on proliferation of OS cells after OS cells treated with 25 <i>μ</i>g/ml miR-NC inhibitor+OS-Exos or 25 <i>μ</i>g/ml miR-1307 inhibitor+OS-Exos were assayed by CCK-8. (e–i) Effects on migration and invasion of OS cells after OS cells treated with 25 <i>μ</i>g/ml miR-NC inhibitor+OS-Exos or 25 <i>μ</i>g/ml miR-1307 inhibitor+OS-Exos were assayed by Transwell. 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BioMed Research International

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Figure 6

Figure 6: Osteosarcoma Cell-Derived Exosomal miR-1307 Promotes Tumorgenesis via Targeting AGAP1 