Research Article

[Retracted] The Influence of ICAM1 3′UTR Gene Polymorphism on the Occurrence and Metastasis of Primary Liver Cancer

Table 5

Stratified analysis of the correlation between SNP at rs281437 locus of the ICAM1 gene and PHC susceptibility risk.

PHC ()Control ()OR (95% CI) value

Age [years, (%)]
 <60
  CC82 (60.29%)114 (81.43%)1.00 (reference)
  CT+TT54 (39.71%)26 (18.57%)2.89 (1.67-4.99)<0.01
 ≥60
  CC95 (61.69%)116 (77.33%)1.00 (reference)
  CT+TT59 (38.31%)34 (22.67%)2.12 (1.28-3.50)<0.01
Gender [ (%)]
 Male
  CC111 (68.10%)127 (76.51%)1.00 (reference)
  CT+TT52 (31.90%)39 (23.49%)1.53 (0.94-2.48)0.11
 Female
  CC66 (1.97%)103 (83.06%)1.00 (reference)
  CT+TT61 (48.03%)21 (16.94%)4.53 (2.53-8.13)<0.01
BMI [kg/m2, (%)]
 <25
  CC85 (57.82%)136 (77.71%)1.00 (reference)
  CT+TT62 (42.18%)39 (22.29%)2.54 (1.57-4.13)<0.01
 ≥25
  CC92 (64.34%)94 (81.74%)1.00 (reference)
  CT+TT51 (35.66%)21 (18.26%)2.48 (1.38-4.45)<0.01
Smoking [ (%)]
 No
  CC72 (57.60%)129 (71.14%)1.00 (reference)
  CT+TT53 (42.40%)45 (25.86%)2.11 (1.29-3.45)<0.01
 Yes
  CC105 (63.64%)101 (87.07%)1.00 (reference)
  CT+TT60 (36.36%)15 (12.93%)3.85 (2.05-7.21)<0.01
Drinking [ (%)]
 No
  CC79 (66.39%)127 (81.41%)1.00 (reference)
  CT+TT40 (33.61%)29 (18.59%)2.22 (1.27-3.86)<0.01
 Yes
  CC98 (57.31%)103 (76.87%)1.00 (reference)
  CT+TT73 (42.69%)31 (23.13%)2.48 (1.50-4.09)<0.01
Family history of cancer [ (%)]
 No
  CC141 (60.00%)220 (79.14%)1.00 (reference)
  CT+TT94 (40.00%)58 (20.86%)2.53 (1.71-3.73)<0.01
 Yes
  CC36 (65.45%)10 (83.33%)1.00 (reference)
  CT+TT19 (34.55%)2 (16.67%)2.64 (0.52-13.29)0.39
Hepatitis B virus [ (%)]
 Negative
  CC31 (58.49%)202 (79.22%)1.00 (reference)
  CT+TT22 (41.51%)53 (20.78%)2.71 (1.45-5.05)<0.01
 Positive
  CC146 (61.60%)28 (80.00%)1.00 (reference)
  CT+TT91 (38.40%)7 (20.00%)2.49 (1.05-5.94)0.03

Adjust factors such as BMI, smoking, drinking, family history of tumors, and hepatitis B virus. OR: odds ratio; CI: confidence interval.