MicroRNA-103a-3p Promotes Cell Proliferation and Invasion in Non-Small-Cell Lung Cancer Cells through Akt Pathway by Targeting PTEN

Figure 2

PTEN is a target gene of miR-103a-3p. (a) Sequence diagram of miR-103a-3p with its binding site in PTEN 3-UTR. (b) Luciferase reporter assay detection for HEK293T transfected with miR-103a-3p mimics or PTEN-WT or PTEN-MUT. Effect of miR-103a-3p on PTEN mRNA (c) and protein (d) expressions was detected by qRT-PCR and western blot (, ).

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